磁性纳米粒子的合成及其生物医学应用研究进展

Synthesis and Biomedical Applications of Magnetic Nanoparticles

磁性纳米粒子是一种发展迅速的新型功能材料, 在生物医学领域具有很高的应用价值, 由于其具有大的比表面积、强的磁响应性、良好的生物相容性和独特的超顺磁性, 被广泛应用于磁性分离、磁性转染、磁热疗、磁性药物靶向载体和纯化等方面。本文概括了磁性纳米粒子的制备方法和表面改性技术, 并论述了磁性纳米粒子在生物医学领域的应用与发展。

Magnetic nanoparticles are a new type of functional material that develops rapidly and has high application value. Because of their high specific surface area, strong magnetic responsiveness, excellent biocompatibility and typical superparamagnetism, they have been widely used in the field of biomedical applications including magnetic separation, magnetic transfection, magnetic hyperthermia, magnetic targeting drug carrier and purification. In this paper, the preparative methods and surface modification techniques of magnetic nanoparticles were summarized, and the application and development of magnetic nanoparticles in the field of biomedicine were discussed.