美白祛斑经方与验方的传承与现代化研究

凌晓芬; LING Xiaofen; 黄颖琦; HUANG Yingqi; 陈晓燕; CHEN Xiaoyan; 林伟俊; LIN Weijun; 谢志辉; XIE Zhihui; 詹雅娴; ZHAN Yaxian

doi:10.48014/atcm.20251010002

美白祛斑经方与验方的传承与现代化研究

Research on the Inheritance and Modernization of Traditional and Proven Formulas for Whitening and Removing Spots

中医药研究进展 2025年第1卷第3期页码[30-39] 下载全文[1.2MB]

摘要

皮肤色素沉着过度引发的黄褐斑、雀斑等色斑是常见损容性皮肤病, 既影响外观、打击患者自信心, 又加重其社会交往负担, 安全有效的美白祛斑已成为全球性健康与美容诉求。中医药凭借整体观与辨证论治特色, 在该领域展现独特优势。中医将皮肤色素问题归为“黄褐斑”“黧黑斑”“面尘”等范畴, 认为与肝、脾、肾功能失常、气血不和等相关, 历代医家创制了调理气血、疏肝解郁等各类经方验方, 依君臣佐使配伍, 实现“以内养外”的疗效。但传统方剂存在作用机制不明确等局限, 现代科技发展与需求升级为其转化带来机遇与挑战。本文系统梳理中医美白祛斑代表性经方验方, 探讨其组方原理、传统功效与现代药理基础, 重点分析经典应用与现代实践中的关键改进及转化策略, 总结古今融合的经验与挑战, 为方剂的现代化、科学化、国际化应用提供改进思路与理论依据, 助力中医药在皮肤美容领域的传承创新, 满足人们安全高效的美肤需求。

Abstract

Hyperpigmentation-induced skin conditions such as chloasma and freckles are common disfiguring skin diseases, which not only affect appearance and undermine patients' confidence but also increases the burden of social interaction. Safe and effective skin whitening and spot removal have become a global health and beauty concern. Traditional Chinese medicine (TCM) , with its holistic view and syndrome differentiation and treatment characteristics, has shown unique advantages in this field. In traditional Chinese medicine, skin pigmentation problems are classified into categories such as “chloasma”, “melanosis”, and “facial dust”, and are believed to be related to liver, spleen, and kidney dysfunction, as well as the imbalance of qi and blood. Throughout history, TCM practitioners have created various classic and empirical prescriptions for regulating qi and blood and soothing the liver and relieving depression, following the principle of the sovereign, minister, assistant, and courier ingredients, to achieve the effect of “nourishing the exterior from within”. However, traditional prescriptions have limitations such as unclear mechanisms of action. The development of modern science and technology and the upgrading of demands bring both opportunities and challenges for their transformation. This article systematically reviews representative TCM classic and empirical prescriptions for skin whitening and spot removal, explores their composition principles, traditional functions, and modern pharmacological foundations, and highlights key improvements and transformation strategies in classical applications and modern practices. It summarizes the experiences and challenges of integrating ancient and modern knowledge, providing insights and theoretical basis for the modernization, scientific validation and international application of these prescriptions, and promoting the inheritance and innovation of TCM in the field of skin beauty, to meet people' s demands for safe and efficient skin care.

DOI

10.48014/atcm.20251010002

文章类型

综述

收稿日期

2025-10-10

接收日期

2025-11-17

出版日期

2025-12-28

关键词

中医美白, 美白祛斑, 黄褐斑, 经方验方

Keywords

Traditional Chinese medical cosmetology, whiten and remove freckles, classical prescriptions and empirical prescriptions

作者

凌晓芬¹, 黄颖琦¹, 陈晓燕¹, 林伟俊^1,3, 谢志辉^3,*, 詹雅娴^1,2,*

Author

LING Xiaofen¹, HUANG Yingqi¹, CHEN Xiaoyan¹, LIN Weijun^1,3, XIE Zhihui^3,*, ZHAN Yaxian^1,2,*

所在单位

1. 广州中医药大学中药学院岭南中药资源教育部重点实验室, 广州 510006
2. 中医药慢病防治广东省普通高校重点实验室, 广州 510006
3. 谢志辉生物医药研究院 (广州) 有限公司, 广州 510006

Company

1. Key Laboratory of Chinese Medicinal Resource from Lingnan, Ministry of Education, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
2. Key Laboratory of Traditional Chinese Medicine for Chronic Disease Prevention and Control, Guangdong Provincial Colleges and Universities, Guangzhou 510006, China
3. Xie Zhihui Biomedical Research Institute Guangzhou Co. Ltd, Guangzhou 510006, China

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基金项目

本项研究得到了“中草药在化妆品中的作用机制与应用研究”基金(资助号:E4-6401-243-112-002)、广州中医药大学科技成果孵化项目(资助号:GZYFH2025Z01)资助。

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引用本文

凌晓芬,黄颖琦,陈晓燕,等.美白祛斑经方与验方的传承与现代化研究[J].中医药研究进展,2025,1(3):30-39.

Citation

LING Xiaofen, HUANG Yingqi, CHEN Xiaoyan, et al. Research on the inheritance and modernization of traditional and proven formulas for whitening and removing spots[J]. Advances in Traditional Chinese Medicine, 2025, 1(3): 30-39.