The traditional “teaching style” teaching model is led by teachers who impart knowledge to students, while students thinking and practical abilities are not fully utilized. With the progress of the times and the updating of educational concepts, traditional teaching models urgently need to be reformed to meet the needs of modern education, and the “guided learning” teaching model has emerged. In the “guided learning” teaching mode, the role of the teacher undergoes a transformation. The teacher guides students to learn and explore, and under the teaching conditions and reasonable guidance provided by the teacher, students engage in group learning and teamwork through self-directed learning and practice, exerting their thinking and innovation abilities, discovering and solving problems, and thus better mastering knowledge and skills. The “guided learning” teaching model is based on constructivist theory and zone of proximal development theory as its core foundation. Students take the initiative to construct and teachers design problem chains to build learning scaffolds, guiding students to cross cognitive intervals from independent exploration and achieving a student-centered and teacher guided teaching model. The “guided learning” teaching model emphasizes the cultivation of students autonomous learning and practical abilities. Its purpose is to establish a guidance for autonomous learning, introduce cooperative learning methods, and adopt various teaching methods to achieve the goal of cultivating innovative thinking and practical abilities of students majoring in traditional Chinese medicine, and comprehensively cultivate talents in traditional Chinese medicine.