The problems existing in the life safety education of contemporary rural teenagers are mainly manifested as life safety problems and mental health problems, and there are three main reasons for these problems, namely, the rural teenagers’ own level, school level and society level. In addition, specific and feasible solutions are put forward to address the existing life safety problems and mental health problems, that is to give play to the role of main school and teachers in all subjects, attach importance to physical education and mental health classes, and strengthen the cooperation between schools and parents to achieve the cooperation between home and school, so that we can jointly strengthen life safety education for rural teenagers and promote their healthy growth.